any city too big, largest city I’ve been to currently is Oslo and of course that’s our capital city in Norway (I’m Northern Norwegian). Somewhere I don’t know the official language or most of the people there cannot speak English with me. Anywhere too hot/warm; that’s actually the biggest problem of all the examples here. I’m a Northern person who is naturally warm even in really cold (like -25°C outside) winter season weather, my cousin calls me ‘radiator’ so even in our town when we get 30°C in summer I’m just very fatigued and uncomfortable.
but in general all places have some good aspects to them and that’s what really matters.